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Michael Somenek, a clinical investigator in the groundbreaking Galderma study, notes that as medication-driven weight loss becomes more prolific around the world, so do the associated impacts of facial volume loss and other unwanted cosmetic effects like shadowing and hollowness. The Science Behind Facial Changes with GLP-1 Medications The 2025 Galderma clinical trial confirms what weve been observing in our practice at Aestha Clinic

The researchers who get the best long-term results are almost always the ones who can tolerate weeks of minimal scale movement without abandoning the protocol

This makes Wegovy the first weight-loss medication licensed in the UK to reduce the risk of serious cardiovascular events

Muriach M, Flores-Bellver M, Romero FJ et al (2014) Diabetes and the brain: oxidative stress, inflammation, and autophagy

However, if you have a sensitive stomach, taking it shortly after a light meal can help mitigate any potential discomfort